Guideline on the evaluation of medicinal products for the treatment of chronic constipation (including opoid induced constipation) and other bowel cleansing

Evaluation of Immunohistochemistry (IHC) in Children with Chronic Constipation

Introduction Constipation is one of the most common causes of referral to pediatric gastroenterology clinics. The histopathology and Immunohistochemistry (IHC) studies indicated that several neurons are currently detectable in motility of the gut. We aimed to evaluate calretinin in the children with chronic constipation. Materials and Methods In this cohort study, 40 children with chronic const...

Guideline on the evaluation of medicinal products for the treatment of chronic constipation (EMA/CHMP/336243/2013)

Challenges and New Treatment in Childhood Constipation

Chronic Constipation is a debilitating condition that is often associated with different abdominal problem. It can cause distress for the child and family and can result in emotional disturbance and family problem. Based on the current algorhytm, the treatment of chronic constipation consists of 4 important phases, 1: education, 2: disimpaction, 3: prevention of re-accumulation of feces and 4: ...

Effect of an herbal capsule on chronic constipation among menopausal women: A randomized controlled clinical trial

Objective: Chronic constipation is frequently observed in postmenopausal women. An herbal combination including clover plants, Roman anis or Anisone, green anis or fennel, green raisins, Alhagi maurorum, violets, Terminalia chebula, senna and golqand has been introduced in traditional books as an effective laxative. Thus, the present study aimed to assess the effectiveness of t...

Relationship of constipation and irritable bowel syndrome with food intake, anthropometric measurements and eating behaviors in male students

Background and Objectives: Gastrointestinal disorders like irritable bowel syndrome (IBS) and constipation can affect the quality of life and various factors play a role in these disorders. The aim of this study was to investigate the environmental factors related to these problems among Iranian male university students. Materials and Methods: The study was conducted on 186 male students at ...